Imaging cells in real time can provide critical insights into the nature of biological cell and tissue function. At the centre we have a number of options for microscopes fitted with environmental chambers. These chambers can tightly control the temperature and humidity and CO2 levels so that living cells can be maintained in a healthy state during long term imaging experiments. The chambers are fixed and cover the whole microscope station. The system is also fitted with a zero drift compensation (zdc) system to prevent focal drift during long term imaging. Volocity software is available for 2D and 3D analysis of image data.